Compile Data Set for Download or QSAR
maximum 50k data
Found 523 of ic50 data for polymerid = 5445,9915,50002467
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035236(3-(2-Hydroxycarbamoyl-3-methyl-butyrylamino)-propi...)
Affinity DataIC50:  0.0100nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035247(2-(2-Hydroxycarbamoyl-3-methyl-butyrylamino)-3-(1H...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035246(2-(2-Hydroxycarbamoyl-4-methyl-pentanoylamino)-3-(...)
Affinity DataIC50:  0.25nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035239(CHEMBL63317 | N-[1-Carbamoyl-2-(1H-indol-3-yl)-eth...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046841(CHEMBL357864 | Morpholine-4-carboxylic acid {2-cyc...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50084905(CHEMBL147964 | {1-[2-Dibenzofuran-3-yl-1-(1H-tetra...)
Affinity DataIC50:  2.60nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50084905(CHEMBL147964 | {1-[2-Dibenzofuran-3-yl-1-(1H-tetra...)
Affinity DataIC50:  2.60nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035251(2-(2-Hydroxycarbamoyl-3-methyl-butyrylamino)-succi...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407080(CHEMBL2112254)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368802(CHEMBL1791097)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407074(CHEMBL2112267)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407089(CHEMBL2112253)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035249(CHEMBL303892 | N-[1-Carbamoyl-2-(1H-indol-3-yl)-et...)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407087(CHEMBL2112258)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407076(CHEMBL2112270)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407075(CHEMBL2112262)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407070(CHEMBL2112268)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046820(4-Methyl-piperazine-1-carboxylic acid {2-cyclohexy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50084903(CHEMBL148056 | {[2-Dibenzofuran-3-yl-1-(1H-tetrazo...)
Affinity DataIC50:  6nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407071(CHEMBL2112257)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50084897(3-Dibenzofuran-3-yl-2-[3-dibenzofuran-3-yl-2-(phos...)
Affinity DataIC50:  6.40nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368795(CHEMBL1791129)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035240((2-Hydroxycarbamoyl-3-methyl-butyrylamino)-acetic ...)
Affinity DataIC50:  6.80nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368810(CHEMBL1791125)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407072(CHEMBL2112269)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50064110(2-{2-[(S)-5-(2,4-Difluoro-phenyl)-2-(phosphonometh...)
Affinity DataIC50:  8nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50119751(2-{[1-(2-Mercapto-4-methyl-pentanoylamino)-cyclope...)
Affinity DataIC50:  9.5nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50119742(2-{[1-(2-Mercapto-4-methyl-pentanoylamino)-cyclope...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of Homo sapiens (human) endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50119742(2-{[1-(2-Mercapto-4-methyl-pentanoylamino)-cyclope...)
Affinity DataIC50:  9.80nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM97371(ECE Inhibitor, 14)
Affinity DataIC50:  10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50171626(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)
Affinity DataIC50:  10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50159365((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...)
Affinity DataIC50:  10.4nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368814(CHEMBL1791126)
Affinity DataIC50:  11nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407088(CHEMBL2112255)
Affinity DataIC50:  11nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50368798(CHEMBL1791120)
Affinity DataIC50:  11nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50488971(CHEMBL2297562)
Affinity DataIC50:  11nMAssay Description:Inhibition of Homo sapiens (human) endothelin converting enzyme-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50091882((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-1-oxo-pe...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of Endothelin-converting enzyme 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50091882((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-1-oxo-pe...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity was tested against Endothelin converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50091878((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methox...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of human Endothelin converting Enzyme-1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035235(CHEMBL2372437 | N-[1-(Carbamoylmethyl-carbamoyl)-e...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50488983(CHEMBL2297552)
Affinity DataIC50:  11nMAssay Description:Inhibition of Homo sapiens (human) endothelin converting enzyme-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50091882((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-1-oxo-pe...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of human Endothelin converting Enzyme-1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50098118((2S,4R)-4-Mercapto-2-(2,4,5-trifluoro-benzyloxymet...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50407086(CHEMBL2112265)
Affinity DataIC50:  12nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50064114((S)-3-Biphenyl-4-yl-2-[(S)-5-(2-fluoro-phenyl)-2-(...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50084898(2-[3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-p...)
Affinity DataIC50:  13nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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